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Search Results for " xanthine oxidase "

20

Compounds

Cat No. Product Name Synonyms Targets
T76104 Xanthine oxidase
Xanthine oxidase, a xanthine oxidoreductase enzyme, catalyzes the oxidation of hypoxanthine to xanthine and further oxidizes xanthine to uric acid, generating reactive oxygen species (ROS) [1].
T10509 Xanthine oxidase-IN-1 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid Xanthine Oxidase
Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM. It plays a central role in purine catabolism through the degradation of bioactive nucleotides facilitated by nucleic acid ...
T78984 Xanthine oxidase-IN-10 XO8 analog ROS
Xanthine oxidase-IN-10 (XO8 analog) is a xanthine oxidase (XO) inhibitor for the study of gout.
T16685 Purpurogallin Xanthine Oxidase
Purpurogallin is a naturally phenol extracted from the plants of Quercus spp. It has effective xanthine oxidase inhibitory activity (IC50: 0.2 µM). Purpurogallin also has antioxidant and anti-inflammatory effects.
T1694 Oxypurinol Oxipurinol ROS , Xanthine Oxidase , Endogenous Metabolite
Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure.
T8337 Nequinate Xanthine Oxidase , Parasite
Nequinate is an anticoccidial agent, preventing coccidiosis .
TMA0958 Forsythoside F Arenarioside Xanthine Oxidase
Forsythoside F (Arenarioside) is a natural product, and GI50 values of 10-16 microM against B16F10 cell.
T1274 Benzbromarone Desuric,Normurat,Urinorm Apoptosis , P450 , Xanthine Oxidase
Benzbromarone (Desuric) is a CYP2C9 inhibitor with Ki value of 19.3 nM.
T2858 Baicalein 5,6,7-Trihydroxyflavone Ferroptosis , Influenza Virus , ROS , Xanthine Oxidase
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.
T75504 Xanthine oxidase-IN-8
Xanthine oxidase-IN-8 (Icarisids J) (Compound 7) serves as an inhibitor of xanthine oxidase, exhibiting an inhibitory concentration (IC50) value of 29.71 μM [1].
T60626 Xanthine oxidase-IN-7
Xanthine oxidase-IN-7 (compound1h) is a potent andorally active xanthine oxidase(XO) inhibitor (IC50 = 0.36 μM). Xanthine oxidase-IN-7 effectively reduces serum uric acid levels which has the potential in the hyperuricem...
T22304 Desciclovir BW A515U,6-Deoxyacyclovir,DCV Antifection
Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.
T61092 Xanthine oxidase-IN-5
Xanthine oxidase-IN-5, a powerful and orally active inhibitor of xanthine oxidase (XO), exhibits an IC50 value of 0.70 μM. It possesses favorable drug-like characteristics, with ligand efficiency (LE) and lipophilic liga...
T75505 Xanthine oxidase-IN-9
Xanthine Oxidase-IN-9 (also known as Icarisids E or Compound 2) effectively inhibits xanthine oxidase (XOD) with an IC50 value of 31.81 μM [1].
T72409 Xanthine oxidase-IN-6
Xanthine oxidase-IN-6, a potent and orally active mixed-type inhibitor of xanthine oxidase (XOD), demonstrates significant anti-hyperuricemia and renal protective activity with an IC50 value of 1.37 µM.
T60632 Xanthine oxidase-IN-4
Xanthine oxidase-IN-4 (compound 19a) is an orally active and potent inhibitor of xanthine oxidase(XO) with an IC 50 of 0.039 μM that can be used in the research of hyperuricemia and gout. Xanthine oxidase-IN-4 shows hypo...
T78985 Xanthine oxidase-IN-11 Xanthine Oxidase
Xanthine Oxidase-IN-11, an analog of XO8, is an inhibitor of xanthine oxidase (XO) [1].
T80767 Xanthine oxidase-IN-12 Xanthine Oxidase
Xanthine oxidase-IN-12 (Compound 11), an inhibitor of xanthine oxidase (XO), possesses an IC50 value of 91 nM and exhibits antioxidant properties, additionally diminishing intracellular reactive oxygen species (ROS) [1].
T2397 Topiroxostat FYX-051 P450 , ROS , Xanthine Oxidase
Topiroxostat (FYX-051) is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout.
T12564 Prudomestin 3,5,7-Trihydroxy-4',8-dimethoxyflavone Xanthine Oxidase
Prudomestin (3,5,7-Trihydroxy-4',8-dimethoxyflavone) is a natural product isolated from the heartwood of Prunus domestica, with xanthine oxidase (XO) inhibitory activity with IC50 of 6 µM.
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TargetMol