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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T76104 | Xanthine oxidase | ||
Xanthine oxidase, a xanthine oxidoreductase enzyme, catalyzes the oxidation of hypoxanthine to xanthine and further oxidizes xanthine to uric acid, generating reactive oxygen species (ROS) [1]. | |||
T10509 | Xanthine oxidase-IN-1 | 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid | Xanthine Oxidase |
Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM. It plays a central role in purine catabolism through the degradation of bioactive nucleotides facilitated by nucleic acid ... | |||
T78984 | Xanthine oxidase-IN-10 | XO8 analog | ROS |
Xanthine oxidase-IN-10 (XO8 analog) is a xanthine oxidase (XO) inhibitor for the study of gout. | |||
T16685 | Purpurogallin | Xanthine Oxidase | |
Purpurogallin is a naturally phenol extracted from the plants of Quercus spp. It has effective xanthine oxidase inhibitory activity (IC50: 0.2 µM). Purpurogallin also has antioxidant and anti-inflammatory effects. | |||
T1694 | Oxypurinol | Oxipurinol | ROS , Xanthine Oxidase , Endogenous Metabolite |
Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure. | |||
T8337 | Nequinate | Xanthine Oxidase , Parasite | |
Nequinate is an anticoccidial agent, preventing coccidiosis . | |||
TMA0958 | Forsythoside F | Arenarioside | Xanthine Oxidase |
Forsythoside F (Arenarioside) is a natural product, and GI50 values of 10-16 microM against B16F10 cell. | |||
T1274 | Benzbromarone | Desuric,Normurat,Urinorm | Apoptosis , P450 , Xanthine Oxidase |
Benzbromarone (Desuric) is a CYP2C9 inhibitor with Ki value of 19.3 nM. | |||
T2858 | Baicalein | 5,6,7-Trihydroxyflavone | Ferroptosis , Influenza Virus , ROS , Xanthine Oxidase |
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor. | |||
T75504 | Xanthine oxidase-IN-8 | ||
Xanthine oxidase-IN-8 (Icarisids J) (Compound 7) serves as an inhibitor of xanthine oxidase, exhibiting an inhibitory concentration (IC50) value of 29.71 μM [1]. | |||
T60626 | Xanthine oxidase-IN-7 | ||
Xanthine oxidase-IN-7 (compound1h) is a potent andorally active xanthine oxidase(XO) inhibitor (IC50 = 0.36 μM). Xanthine oxidase-IN-7 effectively reduces serum uric acid levels which has the potential in the hyperuricem... | |||
T22304 | Desciclovir | BW A515U,6-Deoxyacyclovir,DCV | Antifection |
Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase. | |||
T61092 | Xanthine oxidase-IN-5 | ||
Xanthine oxidase-IN-5, a powerful and orally active inhibitor of xanthine oxidase (XO), exhibits an IC50 value of 0.70 μM. It possesses favorable drug-like characteristics, with ligand efficiency (LE) and lipophilic liga... | |||
T75505 | Xanthine oxidase-IN-9 | ||
Xanthine Oxidase-IN-9 (also known as Icarisids E or Compound 2) effectively inhibits xanthine oxidase (XOD) with an IC50 value of 31.81 μM [1]. | |||
T72409 | Xanthine oxidase-IN-6 | ||
Xanthine oxidase-IN-6, a potent and orally active mixed-type inhibitor of xanthine oxidase (XOD), demonstrates significant anti-hyperuricemia and renal protective activity with an IC50 value of 1.37 µM. | |||
T60632 | Xanthine oxidase-IN-4 | ||
Xanthine oxidase-IN-4 (compound 19a) is an orally active and potent inhibitor of xanthine oxidase(XO) with an IC 50 of 0.039 μM that can be used in the research of hyperuricemia and gout. Xanthine oxidase-IN-4 shows hypo... | |||
T78985 | Xanthine oxidase-IN-11 | Xanthine Oxidase | |
Xanthine Oxidase-IN-11, an analog of XO8, is an inhibitor of xanthine oxidase (XO) [1]. | |||
T80767 | Xanthine oxidase-IN-12 | Xanthine Oxidase | |
Xanthine oxidase-IN-12 (Compound 11), an inhibitor of xanthine oxidase (XO), possesses an IC50 value of 91 nM and exhibits antioxidant properties, additionally diminishing intracellular reactive oxygen species (ROS) [1]. | |||
T2397 | Topiroxostat | FYX-051 | P450 , ROS , Xanthine Oxidase |
Topiroxostat (FYX-051) is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout. | |||
T12564 | Prudomestin | 3,5,7-Trihydroxy-4',8-dimethoxyflavone | Xanthine Oxidase |
Prudomestin (3,5,7-Trihydroxy-4',8-dimethoxyflavone) is a natural product isolated from the heartwood of Prunus domestica, with xanthine oxidase (XO) inhibitory activity with IC50 of 6 µM. |